Novel Mitral Valve Repair Device:
Concept Launch

Investigators Meeting
May 27, 2005
Zagreb, Croatia

Chairman: Bojan Biocina, MD, PhD - Associate
Professor of Surgery, Health Polytechnic, Zagreb

FINAL PROGRAM

Moderator: Prof. Marko Turina, MD, PhD
University Hospital, Zurich - Switzerland

7:00am Breakfast
7:30am Welcome and opening remarks
Bojan Biocina, MD, PhD - University of Zagreb/Dubrava Hospital Zagreb - Croatia

7:35am Rationale for the MF concept
Shlomo Gabbay, MD UMDNJ Medical School, New Jersey and Shelhigh, Inc.

7:50am Mitral valve surgery: Long-term results - Repair versus replacement.
David H. Adams, MD/ Lishan Aklog, MD, Mt. Sinai Medical Center, New York City - USA

8:05am Clinical evaluation of the MF sizer:
Can it be used for conventional mitral valve repair?
Frank Oertel, MD - Klinikum Nürnberg Süd, Nürnberg - Germany

8:15am Preliminary clinical results with the MF device.
Protocol: Review of results and inclusion/exclusion criteria (first 10 cases).
Bojan Biocina, MD, PhD - University of Zagreb/Dubrava Hospital Zagreb - Croatia
Discussion

8:40am Anesthesiology/perioperative echo
Nada Nikic, MD, - University of Zagreb / Dubrava Hospital Zagreb - Croatia

8:50am Clinical results of mitral valve repair for degenerative mitral valve
disease versus ischemic mitral regurgitation. (Restricted motion of the
posterior leaflet)
Thomas Walter MD, PhD/ Prof. Friedrich Mohr - Heart Center University of Leipzig - Germany

9:00am Clinical results of mitral valve repair for ischemic mitral regurgitation
Michele Musci, MD / Prof. Roland Hetzer, MD, PhD. - German Heart Center, Berlin - Germany

Discussion

9:10am The Munich experience with mitral valve repair.
Herbert Augustin, MD, PhD / Prof. Ruediger Lange - German Heart Center - Technical University of the State of Bavaria Munich - Germany

9:20am Patient ready to go on bypass

9:25am MF device implantation/ live surgery transmission from Dubrava University Hospital
Bojan Biocina, MD, PhD Zagreb, Croatia will be assisted by one or two of the
investigators. Interaction / Q&A between the surgeon and the audience during
the implantation procedure

11:10am CASE DISCUSSION following the implantation.
Bojan Biocina, MD, PhD - Questions & Answers

11:25am Cardiologist review of pre and post operative 2D echocardiography
Discussion of proper patient selection for MF device implantation
Danijel Planinc, MD, Boris Starcevic, MD / Drazen Sebetic, MD, University of Zagreb Dubrava Hospital, Zagreb - Croatia

11:40pm Towards routine mini mitral repair with a new enabling platform
Didier de Canniere MD PhD Hôpital Erasme Brussels - Belgium/ Olivier J. L. Jegaden MD,
Hôpital Cardiothoracique Louis Pradel, Lyon-Bron - France

12:00pm LUNCH

1:00pm Current State of Mitral Valve Repair
Moderator: Prof. Borut Gersak, MD, PhD University Medical Center, Ljubljana - Slovenia

1:05pm Minimally invasive, endoscopic, port-access, mitral valve repair.
Prof. Borut Gersak, MD, PhD, University Medical Center Ljubljana - Slovenia

1:15pm The Chicago and Loyola experience of mitral valve repair for degenerative
and ischemic mitral regurgitation.
Marc Gerdisch, MD/M. Bakhos, MD - Loyola University Medical Center, Chicago - USA

1:25pm Posterior mitral leaflet extension: A new adjunctive repair option for ischemic
mitral regurgitation?
Frank Langer, MD / Prof. Hans-Joachim Shaefers, MD - University Hospital Saarlandes,
Homburg/ Saar - Germany

1:35pm Mitral Valve Repair - The Zwolle Experience
Hauw T. Sie, MD - Isala Klinieken, Zwolle - Netherlands

1:50pm Review of clinical study protocol / regulatory issues.
Curtis Truesdale, Manager of Regulatory Affairs, Shelhigh, Inc., Union, New Jersey - USA

Discussion

2:05pm WET LAB - Pig heart implantation of the MF device . All investigators will
have an opportunity to implant one MF device.
Moderators: Bojan Biocina, MD, PhD and Shlomo Gabbay, MD

3:15pm Panel Discussion
Moderator: Prof. Marko Turina, MD, PhD University Hospital, Zurich

4:15pm MEETING ADJOURNED